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153-98-0

Serotonin Hydrochloride

Serotonin Hydrochloride

別名:
CasNo.: 153-98-0
分子式: C10H12N2O.HCl
分子量: 212.679
儲存條件:
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中文名稱: Serotonin Hydrochloride
英文名稱: Serotonin Hydrochloride
CasNo.: 153-98-0
分子式: C10H12N2O.HCl
分子量: 212.679

Quality Factory Sells Top Purity 99% Serotonin Hydrochloride 153-98-0 with Safe Delivery

  • Molecular Formula:C10H12N2O.HCl
  • Molecular Weight:212.679
  • Appearance/Colour:white to cream powder 
  • Vapor Pressure:1.63E-07mmHg at 25°C 
  • Melting Point:168-172 °C 
  • Boiling Point:416.1 °C at 760 mmHg 
  • Flash Point:205.4 °C 
  • PSA:62.04000 
  • LogP:2.87700 

Serotonin hydrochloride(Cas 153-98-0) Usage

Biological Activity

Endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo .

Biochem/physiol Actions

Neurotransmitter.

Purification Methods

5-HT is purified by recrystallisation from EtOH/Et2O or Et2O to give the hygroscopic salt. Store it in the dark as it is light sensitive. The free base has m 84-86o (from Et2O). The 5-benzyloxy derivative has m 84-86o (from Et2O). [Ek & Witkop J Am Chem Soc 76 5579 1954, Hamlin & Fischer J Am Chem Soc 73 5007 1951.] The picrate 1H2O has m 196-197.5o (dec with sintering at 160-165o) after crystallisation from Et2O. Serotonin is a natural neurotransmitter [Chuang Life Sci 41 1051 1987]. [Beilstein 22/12 V 16.]

InChI:InChI=1/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H

153-98-0 Relevant articles

Preparation method of 5-hydroxytryptamine hydrochloride

-

Paragraph 0029, (2021/02/10)

The invention discloses a preparation me...

Method for preparing 5-hydroxytryptamine hydrochloride by utilizing enzymatic fermentation liquor containing 5-hydroxytryptamine

-

Paragraph 0032; 0035-0037; 0038; 0041-0043; 0044; 0047-0049, (2021/02/13)

The invention discloses a method for pre...

153-98-0 Process route

C<sub>10</sub>H<sub>10</sub>N<sub>2</sub>O<sub>3</sub>

C10H10N2O3

serotonin hydrochloride
153-98-0,21591-86-6

serotonin hydrochloride

Conditions
Conditions Yield
C10H10N2O3; With hydrogen; In methanol; at 30 ℃; Autoclave; Industrial scale;
With hydrogenchloride; In methanol; water; Autoclave; Industrial scale;
91%
tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate
53157-48-5

tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate

serotonin hydrochloride
153-98-0,21591-86-6

serotonin hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; In methanol; water; ethyl acetate; at 25 ℃; for 0.166667h;
 

153-98-0 Upstream products

  • 53157-48-5
    53157-48-5

    tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate

153-98-0 Downstream products

  • 53157-48-5
    53157-48-5

    tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate

  • 56-89-3
    56-89-3

    L-cystine

  • 108535-01-9
    108535-01-9

    5,5′-dihydroxy-4,4′-bitryptamine

  • 42241-03-2
    42241-03-2

    4,5-dihydroxytryptamine

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